Sepsis Detection

Sepsis is a life-threatening condition characterized by a dysregulated immune response to infection, leading to organ dysfunction. It is considered a global health concern and a leading cause of death worldwide. Early detection and timely treatment are crucial for improving patient outcomes.

In recent years, there has been increased focus on improving the early detection of sepsis, particularly in non-intensive care settings such as normal wards or low care units. The goal is to identify patients at risk of developing sepsis at an earlier stage, allowing for prompt intervention and treatment.

Under the leadership of Dr. Matthias Gründling, SepsisDialog has been working on the early detection and treatment of sepsis for about 30 years. To improve the outcome and to relieve stationary care, Corsano participated in the price winning smart solution for early detection in patients at risk for sepsis at the normal ward / low care units.  The smart system involves the continuous monitoring of vital signs with CardioWatch 287-2 and the use of advanced algorithms and data analysis to identify early signs of sepsis. By continuously monitoring patients and analyzing relevant data, the system alerts healthcare providers to potential cases of sepsis, enabling early intervention.


Sepsis Facts

Sepsis is a significant cause of mortality globally. It is estimated that sepsis contributes to a substantial number of deaths worldwide each year. According to the Global Burden of Disease Study in 2017, sepsis accounted for approximately 19.7% of all global deaths, representing over 11 million deaths annually.

In Europe, sepsis is recognised as a major public health concern, and efforts are being made to improve sepsis awareness, early recognition, and management.

  • 1 in 5 dies from sepsis
  • Up to 75% has long-term effects
  • Everybody can get sepsis
  • Most sepsis can be treated if detected early

Sepsis Detection System

Using Corsano cardioWatch 287-2 to measure vital signs such as heart rate, blood pressure, temperature, respiratory rate, and oxygen saturation aids in the early detection of sepsis. Changes in these vital signs will indicate physiological distress and will serve as warning signs for the onset of sepsis. Here's how each parameter can be relevant:

Heart Rate: An elevated heart rate, known as tachycardia, can be an early sign of sepsis. Monitoring heart rate trends over time can help identify abnormalities and prompt further evaluation.

Blood Pressure: Sepsis can cause hypotension, or low blood pressure, which is a critical indicator of septic shock. Regular monitoring of blood pressure can help identify sudden drops that may warrant immediate medical attention.

Core Body Temperature: Sepsis can result in either high body temperature (fever) or low body temperature (hypothermia). Monitoring temperature patterns can provide valuable information for early detection.

Respiratory Rate: Rapid or shallow breathing, known as tachypnea or bradypnea, respectively, can be associated with sepsis. Monitoring respiratory rate can help identify abnormal breathing patterns.

Oxygen Saturation: Sepsis can lead to decreased oxygen levels in the blood. Continuous monitoring of oxygen saturation can help detect potential respiratory compromise and the need for supplemental oxygen.

The National Early Warning Score 2 (NEWS2) was used to  determine pattients at risk of sepsis and who require escalated care or intervention.

Artificial Intelligence (AI) was utilized to enhance the system by detecting subtle changes in vital signs or trends that  indicate early signs of deterioration or sepsis. 

The dashboard was developed to provide an overview for each patient to prominently display the patient's NEWS2 score in real-time. By displaying the NEWS2 score and patient vital signs in a well-organized and visually intuitive manner, the dashboard will assist healthcare providers in quickly assessing patient status, identifying deteriorations, and facilitating timely interventions.

SepsisDialog Team

Congratulations with winning the 1st Price! Thank you for the close and efficient collaboration with the entire SepsisDialog Team:

Dr. med. habil. Matthias Gründling

Dr. med. S.-O. Kuhn

Otto Melchert

Guy Delporte

Philipp Müller

Fabian Nokodian

Patrick Böker

Ingo Wloch