Cuffless Non-Invasive Blood Pressure

Cuffless Non-Invasive Blood Pressure

High blood pressure (hypertension) is a common condition in which the long-term force of the blood against the artery walls is high enough that it will eventually cause heart disease with a patient population of 300m+ across the EU and US. Long-term high blood pressure is a major risk factor for stroke, coronary artery disease, heart failure, atrial fibrillation, peripheral arterial disease, vision loss, chronic kidney disease, and dementia. It's often called the "silent killer" because it can exist without any symptoms until it leads to a catastrophic event like a heart attack. Monitoring blood pressure enables cardiologists and physicians to diagnose health problems early. CardioWatch 287-2 enables noninvasive continuous monitoring of blood pressure.

The Corsano Cuffless Non-Invasive Blood Pressure algorithm has been in development since 2019 based on arterial line and ABPM data recorded from over 500 patients. The Corsano Blood Pressure algorithm was validated according to ISO 81060-2:2019 and the AAMI/ESH/ISO collaboration statement “A Universal Standard for the Validation of Blood Pressure Measuring Devices” 2018. Additional validations LONG-TERM, DEVICE POSITION, RE-CALIBRATION, EXERCISE and TREATMENT are ongoing to meet all ESH recommendations.
The research team of the Reinier de Graaf Hospital presented their validation of the Corsano Cuffless Non-Invasive Blood Pressure algorithm at the European Cardiology Congress August 28, 2023.


Patient Outcomes

Benefits of continuous blood pressure monitoring with CardioWatch 287 for patients with hypertension:

Early Detection of Risk: Regular measurement of blood pressure can help identify fluctuations and spikes that may indicate increased risk of health problems, often before they cause symptoms.

Medication Adjustment: The effectiveness of medications to control hypertension can vary from person to person. Regular monitoring can provide data that helps your healthcare provider adjust your medication types or doses to better manage your blood pressure.

Lifestyle Adjustment Evaluation: If the patient is trying to control hypertension with lifestyle changes, such as diet and exercise, daily measurements can help how well efforts are working.

Reducing "White Coat Syndrome": Some people's blood pressure goes up simply because they're in a medical setting. Monitoring blood pressure at home can provide more accurate readings in a relaxed setting, reducing the influence of "white coat syndrome."

Better Engagement with Health: The act of regularly measuring blood pressure can increase a person's engagement with their health and help them feel more in control, which can improve mental health and provide motivation for healthy behaviors.

Early Warning of Hypertensive Crisis: A hypertensive crisis is a severe increase in blood pressure that can lead to a stroke. Extremely high blood pressure — a top number (systolic pressure) of 180 millimeters of mercury (mm Hg) or higher or a bottom number (diastolic pressure) of 120 mm Hg or higher — can damage blood vessels. Daily monitoring can provide early warning signs.

HCP Outcomes

Benefits of CardioWatch 287 for HCP:

  • Improved Patient Adherence as CardioWatch measures automatically versus spot measurements with BP Cuffs that patients often do not want or forget to do.
  • Continuous measurements with SBP and DBP values for each 30 minutes to obtain a view of full 24 hours for patient (similar to ABPM).


  • Long-term measurements to see trends for weeks, months and years.


  • Time saved because no BP Cuff measurement is necessary when patient visit their HCP.


  • Evaluate how SBP and DBP change with medication.
  • Evaluate how SBP and DBP change with personalized advice by HCP on diet, exercise, sleep, and other lifestyle factors that affect health.


Hypertension, or high blood pressure, is a condition in which the force of the blood against the artery walls is too high. Over time, it can cause health issues, including heart disease and stroke. Hypertension is often referred to as a "silent killer" because it doesn't always cause symptoms that would prompt a patient to seek medical attention, but it damages the body and can lead to serious complications.

Heart Disease and Heart Attack: High blood pressure can harden and thicken the heart's arteries, leading to a heart attack. It also puts extra strain on the heart, causing the heart muscle to thicken and become stiffer, which can lead to heart failure.

Stroke: Hypertension is a leading risk factor for both ischemic and hemorrhagic strokes. The high pressure can cause blood vessels to weaken and burst, leading to a hemorrhagic stroke, or become clogged, leading to an ischemic stroke.

Kidney Disease: Hypertension can damage the blood vessels in and around the kidneys, impairing their ability to function effectively. Severe or long-term damage can lead to kidney failure.

Vision Loss: High blood pressure can damage the vessels supplying blood to your retina, causing retinopathy, which can lead to vision loss. It can also lead to fluid buildup under the retina or nerve damage (optic neuropathy).

Sexual Dysfunction: Hypertension can cause erectile dysfunction in men and lower libido in women. This is primarily due to reduced blood flow caused by damaged blood vessels.

Peripheral Artery Disease (PAD): Hypertension is one of the risk factors for PAD, which is a narrowing of peripheral arteries, often in the legs, but also the stomach, arms, and head.

Aneurysm: Over time, the constant pressure of blood moving through a weakened artery can cause a section of its wall to enlarge and form a bulge (aneurysm). Aneurysms can rupture and cause life-threatening internal bleeding.

Cognitive Dysfunction: Hypertension over time can affect your ability to think, remember and learn, leading to mild cognitive impairment and dementia.


Please download the paper via this link