Corsano EndoWatch: The smart wearable that helps to improve life of patients after treatment of a suprasellar brain tumour

Topic
Patients with a suprasellar (hypothalamic) brain tumour often have excellent survival, but poor outcome due to hypothalamic dysfunction (HD). The hypothalamus is an endocrine gland and the key-regulator of our body. It not only regulates the anterior pituitary gland, but also regulates core body temperature, circadian rhythm, sodium and energy balance. Patient s with HD experience chronic fatigue, recurrent headaches and inactivity due to hypothalamic imbalances. Patients develop (morbid) obesity, due to excessive hunger (hyperphagia) and low energy expenditure. Emotional dysregulation can be present. There is currently no treatment for HD. Patients and families urge for a solution.

Number of Participants
50 Patients with hypothalamic dysfunction following brain tumour treatment

Study Design
Recruitment of patients will be done in the Princess Máxima Center for paediatric oncology, where all children in the Netherlands with a brain tumour are treated and followed. Children with hypothalamic dysfunction following brain tumour treatment are seen by a multi-disciplinary expert team led by the paediatric endocrinologist. Currently, more than 100 children with hypothalamic dysfunction are known here. Adult participants will also be recruited in the UMCU, at the department of adult endocrinology. The UMCU is a NFU recognized expertise center for Rare Hypothalamic Disease.

Study Centre
Princess Maxima Center, The Netherlands

Start time, Duration
Start: Q3 2023, Study duration: 12 months

Interested in our Trial Programme?

Corsano Cardiowatch Bracelets enable continuous monitoring with multiple algorithms. Corsano is working closely with cardiologists, scientists, hospitals, patients, and research organisations.  Scientific research demonstrates the legitimacy of Cardiowatch 287 algorithms. 

We are currently performing pilots with selected clients. Contact us if you want to know more!

Corsano CardioWatch is a wrist worn medical grade multi sensor bracelet to capture up to 19 vital parameters. Primary use cases are 24/7 continuous clinical trials and remote patient monitoring.  
 
The bracelet monitor offers flexibility to set data collection intervals by minute, by second or 25Hz, 32 Hz or 128 Hz. We measure Heart Rate, RR intervals, Breathing Rate, A-Fib detection, Skin Temperature, Activity and Sleep. SpO2, Core Body Temperature, ECG and Blood Pressure are in development.  
 
Clinical accuracy is paramount for us. In addition to third parties' algorithms, i.e. from Philips, we run our proprietary algorithms to realize superior data accuracy. Corsano technology has been clinically validated in major academic hospitals. The bracelet is manufactured under ISO 13485 and CE-MDR compliance. The process for FDA Clearance has started. 
 
Our end-to-end solution consists of light-weight and comfortable bracelets with a patient research portal. We have developed and produced over 200’000 devices. The Corsano platform has been optimized on connections, data buffers and battery life up to 15 days. We offer access to raw continuous high frequency data through API and cloud-to-cloud solutions. 
 

The founders of Corsano Health have over 100 years of experience in the Swiss Watch industry, with deep experience about ergonomic design and materials for wearables that are worn 24/7.