The first 1000 days of life reflect the period from the 3 months before conception until the age of 2 years. An accumulating body of evidence suggest that social-demographic background, lifestyle and nutrition of both parents during the preconception and early-pregnancy phases are critical for childhood outcomes. Adverse exposures for the embryo and fetus may lead to developmental adaptations of various organ systems, which are beneficial for short term survival but may lead to adverse health outcomes in later life.
Number of Participants
1750 participating women and 1100 partners (65%)
Women and partners with a desire to have children or early pregnancy are asked to participate in the study during the preconception period or in the first trimester (gestational age < 11 weeks), respectively. They will be asked to wear CardioWatch 287-1. Intervention: Prior to and/or during early pregnancy, investigations will be performed and an intervention will be offered. The intervention group will attend 3 group sessions (interval 4 weeks) focusing on current national advice for preconception and early pregnancy, lifestyle, coping with stress and additional advice regarding diet. The intervention and control group will receive a one-off individual lifestyle consultation in line with the current national advice for preconception and early pregnancy (standard care). This study will primarily focus on the following birth outcomes: preterm birth, birth weight (high/low) and low Apgar score at 5 minutes. Secondary outcomes: (adherence to) lifestyle advice, sleep/wake rhythm, partner support, time to pregnancy, miscarriage, weight gain, stress, hypertension and diabetes during pregnancy, breastfeeding and weight maintenance after pregnancy.
ErasmusMC, Rotterdam, The Netherlands
Start time, Duration
Q1 2023, Duration: 24 months
Interested in our Trial Programme?
Corsano Cardiowatch Bracelets enable continuous monitoring with multiple algorithms. Corsano is working closely with cardiologists, scientists, hospitals, patients, and research organisations. Scientific research demonstrates the legitimacy of Cardiowatch 287 algorithms.
We are currently performing pilots with selected clients. Contact us if you want to know more!
The founders of Corsano Health have over 100 years of experience in the Swiss Watch industry, with deep experience about ergonomic design and materials for wearables that are worn 24/7.